Coiling is a well-preserved behaviour of zebrafish embryos. Since it follows a certain pattern, it can be used to detect changes caused by stressors.
The occurrence of Active Pharmaceutical Ingredients (APIs) is extensively documented in aquatic ecosystems worldwide.
PHARMASEA — Presence, behavior and risk assessment of pharmaceuticals in marine ecosystems — is a European research project that integrates international expertise to answer key research questions on fate and biological effects of active pharmaceutical ingredients (APIs), well recognized contaminants of emerging concern (CECs) for marine ecosystems. PHARMASEA is founded by 2020 AquaticPollutants Joint call of the AquaticPollutants ERA-NET Cofund (GA Nº 869178). This ERA-NET is an integral part of the activities developed by the Water, Oceans and AMR JPIs.